Protein Profiles of Individuals with Erosive Tooth Wear

Abstract Objective: To determine if protein profiles identified in saliva could be used to determine risk and severity of erosive tooth wear. Material and Methods: Three types of saliva sampling were performed to obtain saliva from 34 18-year old individuals that received regular dental check-ups, along with clinical status of the dentition and risk factor related to erosive tooth wear using the VEDE scale. Protein profiles in saliva were determined using electrophoresis and the calculation of the percentage of a specific band at a specific molecular weight in relationship to the total protein in that sample (% of total) using molecular weight standards. This quantification was repeated for each protein band across a range of molecular weights for each sample to test for association with erosive tooth wear status. Results: There were no differences in the number of detectable proteins sourced from the parotid gland, nor the unstimulated and stimulated whole saliva. Five out of the 34 individuals had no signs of erosive tooth wear despite an acidic diet and were more likely to have proteins with molecular weight smaller than 1 KDa (p=0.03). Conclusion: There is potential for the use of protein profiling to determine risks for erosive tooth wear.

Workplace Diesel Exhausts and Gasoline Exposure and Risk of Colorectal Cancer in Four Nordic Countries

BACKGROUND: Evidence on associations between occupational diesel exhaust and gasoline exposure and colorectal cancer is limited. We aimed to assess the effect of workplace exposure to diesel exhaust and gasoline on the risk of colorectal cancer. METHODS: This caseecontrol study included 181,709 colon cancer and 109,227 rectal cancer cases diagnosed between 1961 and 2005 in Finland, Iceland, Norway, and Sweden. Cases and controls were identified from the Nordic Occupational Cancer Study cohort and matched for country, birth year, and sex. Diesel exhaust and gasoline exposure values were assigned by country-specific job-exposure matrices. Odds ratios and 95% confidence intervals were calculated by using conditional logistic regression models. The results were adjusted for physical strain at work and occupational exposure to benzene, formaldehyde, ionizing radiation, chlorinated hydrocarbons, chromium, and wood dust. RESULTS: Diesel exhaust exposure was associated with a small increase in the risk of rectal cancer (odds ratio 1/4 1.05, 95% confidence interval 1.02–1.08). Gasoline exposure was not associated with colorectal cancer risk. CONCLUSION: This study showed a small risk increase for rectal cancer after workplace diesel exhaust exposure. However, this finding could be due to chance, given the limitations of the study.

Improved cardiorespiratory fitness after occupational rehabilitation in merged diagnostic groups

BACKGROUND: Various occupational inpatient rehabilitation programs are established in Norway. This study aimed to assess change in cardiorespiratory fitness, pain, anxiety, depression, and quality of life in persons on long-term sick leave due to musculoskeletal-, mental or unspecific disorders after participation in multicomponent inpatient occupational rehabilitation. METHODS: Twenty-five women and five men (mean age 45.2 years, SD 6.7, range 30–57) volunteered to participate in the study. The participants attended either 8 or 17 full days of occupational multicomponent rehabilitation including physical exercise, cognitive behavioral therapy in the form of acceptance and commitment therapy (ACT), and development of a tailored plan for return to work. Cardiorespiratory fitness was assessed by the Åstrand/Ryhming cycle test at the start and end of rehabilitation program, and at one-year follow-up. Changes in somatic and mental health were measured by questionnaires up to 4 months after start of the program. RESULTS: Linear mixed models showed that the maximal oxygen uptake increased by 1.1 mL°kg-1°min− 1 during the rehabilitation program and by 3.7 mL°kg-1°min− 1 at one-year follow-up. There were minor improvements in somatic and mental health, and quality of life. CONCLUSIONS: This study indicates that occupational inpatient multicomponent rehabilitation including physical exercise and ACT may promote a long-term increase in physical exercise that is sufficient to induce a significant increase in cardiorespiratory fitness. TRIAL REGISTRATION: The current study is not registered, but is part of a larger trial registered at clinicaltrials.gov (No.: NCT01926574, registered 21. Aug 2013).

Interrater reliability of Nursing Activities Score among Intensive Care Unit health professionals / Confiabilidade inter observadores do Nursing Activities Score entre profissionais de saúde da Unidade de Terapia Intensiva / Confiabilidad inter-observador del Nursing Activities Score entre profesionales de la salud en una Unidad de Cuidado Intensivo

ABSTRACT Objective To analyze the interrater reliability of NAS among critical care nurses and managers in an ICU. Method This was a methodological study performed in an adult, general ICU in Norway. In a random selection of patients, the NAS was scored on 101 patients by three raters: a critical care nurse, an ICU physician and a nurse manager. Interrater reliability was analyzed by agreement between groups and kappa statistics. Results The mean NAS were 88.4 (SD=16.2) and 88.7 (SD=24.5) respectively for the critical care nurses and nurse managers. A lower mean of 83.7 (SD=21.1) was found for physicians. The 18 medical interventions showed higher agreement between critical care nurses and physicians (85.6%), than between critical care nurses and nurse managers (78.7). In the five nursing activities the Kappa-coefficients were low for all activities in all compared groups. Conclusion The study indicated a satisfactory agreement of nursing workload between critical care nurses and managers.

RESUMO Objetivo Analisar a confiabilidade interobservadores do NAS entre enfermeiros intensivistas e administradores em UTI. Método Estudo metodológico desenvolvido em UTI geral, de adultos, na Noruega. Em uma amostra selecionada, o NAS foi aplicado em 101 pacientes por três avaliadores: enfermeira assistencial, médico intensivista e enfermeira gestora. A confiabilidade interobservadores foi analisada por meio do teste Kappa. Resultados As médias NAS foram 88,4(SD=16,2) e 88,7(SD=24,5) respectivamente para enfermeiros assistenciais e gestores. Os médicos obtiveram média NAS inferior (83,7; SD=21,1). As 18 intervenções médicas tiveram maior concordância entre enfermeiros assistenciais e médicos (85,6), comparativamente aos enfermeiros assistenciais e gestores (78,7). Nas cinco atividades de enfermagem, os coeficientes Kappa foram baixos em todas as atividades e entre todos os grupos. Conclusão O estudo mostrou confiabilidade interobservadores satisfatória para o NAS entre enfermeiros assistenciais e gestores.

RESUMEN Objetivo : Analizar la confiabilidad inter-observador del NAS entre administradores y enfermeras clínicas en la UCI. Método : Estudio metodológico desarrollado en una UCI general en Noruega. En una muestra seleccionada el NAS fue aplicado en 101 pacientes críticos por tres clases de evaluadores: Enfermeras asistenciales, médicos intensivistas y enfermeras gestoras. La confiabilidad inter-observador fue analizada mediante el test de Kappa. Resultados : Los promedios del NAS fueron 88,4(DE=16,2) y 88,7(DE=24,5) respectivamente para las enfermeras asistenciales y gestoras. Los médicos obtuvieron un promedio NAS inferior 83,7;DE=21,1). Las 18 intervenciones médicas tuvierón mayor concordancia entre las enfermeras asistenciales y los médicos (85,6), en comparación con las enfermeras asistenciales y gestoras (78,7). En las cinco actividades de enfermería, los coeficientes Kappa fueron bajos entodas las actividades y entre todos los grupos. Conclusión : El estudio mostró confiabilidad inter-observador satisfactorias para el NAS entre las enfermeras asistenciales y gestoras.

Hemifacial Transplantation Model in Rats

BACKGROUND: To refine facial transplantation techniques and achieve sound results, it is essential to develop a suitable animal model. Rat is a small animal and has many advantages over other animals that have been used as transplantation models. The purpose of this study was to describe a rat hemifacial transplantation model and to verify its convenience and reproducibility. METHODS: Animals used in this study were Lewis rats (recipients) and Lewis-Brown Norway rats (donors). Nine transplantations were performed, requiring 18 animals. The hemifacial flap that included the ipsilateral ear was harvested based on the unilateral common carotid artery and external jugular vein and was transferred as a single unit. Cyclosporine A therapy was initiated 24 hours after transplantation and lasted for 2 weeks. Signs of rejection responses were evaluated daily. RESULTS: The mean transplantation time was 1 hour 20 minutes. The anatomy of common carotid artery and external jugular vein was consistent, and the vessel size was appropriate for anastomosis. Six of nine allografts remained good viable without vascular problems at the conclusion of study (postoperative 2 weeks). CONCLUSION: The rat hemifacial transplantation model is suitable as a standard transplantation training model.

Hemifacial Transplantation Model in Rats

BACKGROUND: To refine facial transplantation techniques and achieve sound results, it is essential to develop a suitable animal model. Rat is a small animal and has many advantages over other animals that have been used as transplantation models. The purpose of this study was to describe a rat hemifacial transplantation model and to verify its convenience and reproducibility. METHODS: Animals used in this study were Lewis rats (recipients) and Lewis-Brown Norway rats (donors). Nine transplantations were performed, requiring 18 animals. The hemifacial flap that included the ipsilateral ear was harvested based on the unilateral common carotid artery and external jugular vein and was transferred as a single unit. Cyclosporine A therapy was initiated 24 hours after transplantation and lasted for 2 weeks. Signs of rejection responses were evaluated daily. RESULTS: The mean transplantation time was 1 hour 20 minutes. The anatomy of common carotid artery and external jugular vein was consistent, and the vessel size was appropriate for anastomosis. Six of nine allografts remained good viable without vascular problems at the conclusion of study (postoperative 2 weeks). CONCLUSION: The rat hemifacial transplantation model is suitable as a standard transplantation training model.

Nonfatal Occupational Injuries in Norwegian Farmers

BACKGROUND: Agriculture ranks among the most dangerous trades worldwide. There is, however, still a lack of knowledge on nonfatal injuries in agriculture. The aim of this study was to describe the nature and occurrence of nonfatal injuries in farmers in two counties in central Norway. METHODS: A questionnaire was sent to 7,004 farmers in Norway. We asked for information about the respondents and the farm, whether the farmer had had work-related injuries on the farm during the past 12 months, and details about the incidence and seriousness of the injury. RESULTS: A total of 2,699 respondents gave a response rate of 42%. Of the respondents, 249 (9.2%) reported one or more work-related injuries. The most usual cause of injury involved an animal, and >75% of these happened inside the outbuilding. Among these, 17.5% had a consequence of sick leave or a more serious result. When all the accidents were analyzed by stepwise logistic regression, only the variables: works alone, has >3,500 stipulated working hours at the farm, and the type of production were statistical significant explanatory variables for having an injury. CONCLUSION: Incorporating safety aspects to a greater extend in the design and construction of outbuildings would make a substantial contribution to injury prevention in agriculture.

Estágio sanduiche na Noruega: relato de experiência / Sandwich stage in Norway: experience report

O Programa de Doutorado no Brasil com Estágio no Exterior, conhecido como Doutorado Sanduíche, visa a contribuir para intercâmbios dos cursos de Pós-Graduação no País com seus congêneres no exterior. O objetivo deste artigo foi relatar a experiência vivida durante o estágio realizado na Noruega, em unidades hospitalares, laboratórios de microbiologia, órgãos federais e serviços de saúde de Oslo e Região Metropolitana. Foram desenvolvidas atividades de vigilância epidemiológica, técnicas laboratoriais de identificação e tipagem molecular de Staphylococcus aureus e políticas públicas e institucionais de prevenção e controle dessas bactérias, quando multirresistentes. O estágio, além de subsidiar e fortalecer a análise dos dados do projeto da tese, permitiu refletir sobre a importância de políticas públicas e diretrizes definidas, e fornecer condições para ações de prevenção e controle de agravos, tendo a saúde e o bem-estar da pessoa como valores de Estado.

The Doctoral Program in Brazil, with the Internship Abroad known as the Sandwich Ph.D., aims to contribute to exchanges of graduate courses in the country with counterparts abroad. The objective of this article was to report the lived experience during an internship in Norway, in hospital units, microbiology laboratories, federal agencies and health services in Oslo and the metropolitan region. Activities were developed for epidemiological surveillance, laboratory techniques for identification and molecular typing of Staphylococcus aureus, and public and institutional policies for prevention and control of these bacteria, when multiresistant. The Sandwich stage in addition to supporting and strengthening the analysis of project data of the thesis, permitted the reflection on the importance of established public policies and guidelines, and conditions provided for prevention and control of diseases, and health and welfare of the person as values of the state.

El Programa de Doctorado en el Brasil con Prácticas en el Exterior, conocido como Doctorado Sandwich, visa contribuir a los intercambios de los cursos de Postgrado en el País con sus congéneres en el exterior. El objetivo de este artículo fue relatar la experiencia vivida durante las prácticas realizadas en Noruega, en unidades hospitalarias, laboratorios de microbiologia, órganos federales y servicios de salud de Oslo y Región Metropolitana. Se desarrollaron actividades de vigilancia epidemiológica, técnicas de laboratorio de identificación y tipaje molecular de Staphylococcus aureus y políticas públicas e institucionales de prevención y control de esas bacterias, multiresistentes. La práctica, además de ofrecer subsídios y fortalecer al análisis de los datos del proyecto de la tesis, permitió reflexionar sobre la importancia de las políticas públicas y directivas definidas, y dar las condiciones para acciones de prevención y control de agravios, teniendo a la salud y al bienestar de la persona como valores de Estado.

Lessons to learn with the methicillin-resistant Staphylococcus aureus control in Norway

The prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in Norway is low, compared to other European and American countries. The health system includes mandatory case reporting and has written guidelines for prevention and control. This communication describes the national public policies related to MRSA obtained from documents and academic experience gained during a doctoral fellowship in Oslo, Norway. The painstaking procedures used for investigating suspected cases, including health professionals, decolonization and case monitoring, could be important tools to be used by countries with a high prevalence of MRSA.

Terrorism: two complementary approaches / Terrorismo: dos miradas complementarias

Because of the terrorist attacks occurred in Norway on July 22, 2011, this article reviews some critical points of the phenomenon of terrorism. They have risen from social and clinical psychology. From the two disciplines of psychology they have been identified as socio-structural, psychosocial and individual, risk factors. However, in cases such as of Norway, there is a clear demand to the understanding and explanation of violent actions viewed from diverse areas (macro and individual levels) but at the same time complementary to psychology. That can contribute to prevent and/or detect potential attacks to destabilize or manipulate social behavior by using extreme and violent acts that infringe fundamental human rights.

A raíz de los atentados terroristas ocurridos en Noruega el 22 de julio de 2011, el presente artículo hace una revisión de aproximaciones que sobre el fenómeno del terrorismo han sido planteadas desde la psicología social y la psicología clínica. Desde las dos disciplinas de la psicología se identifican algunos factores de riesgo de tipo psicosocial e individual. Sin embargo en casos como el de Noruega, hay una clara demanda a la comprensión y explicación de las acciones violentas, desde áreas diversas (en niveles macrosociales e individuales) complementarias de la psicología, que puedan contribuir a la prevención y/o detección de potenciales atentados que desestabilicen o pretendan manipular comportamientos sociales utilizando medios violentos, extremistas, que lesionan los derechos humanos fundamentales.

Occurrence of Cognitive and Neurological Symptoms in Norwegian Dentists

OBJECTIVES: Previous investigations have presented some evidence of late cognitive effects in dental personnel exposed to metallic mercury. We wanted to examine if Norwegian dentists have an increased prevalence of symptoms consistent with neurological and/or cognitive malfunction. METHODS: The study group consisted of 406 dentists from central Norway and 217 controls from the general population, all under the age of 70. They had responded to a standardised postal questionnaire (Euroquest) inquiring about seven symptoms in regard to neurology, psychosomatics, memory, concentration, mood, sleep disturbances, and fatigue. A score was calculated for each symptom based on 4 to 15 single questions scored on a scale from 1 (seldom or never) to 4 (very often). RESULTS: The dentists and controls had a participation rate of 57.2% and 42.9% respectively. The dentists reported no more cognitive symptoms than the controls, with low average symptom scores from 1.16 for neurological symptoms in males to 1.73 for fatigue in females. Corresponding figures for the controls were 1.22 and 1.77. There were a total of 1.2% of the dentists and 1.8% of the controls who reported having three or more of the seven symptoms "often" or more frequently. CONCLUSION: Norwegian dentists do not report more cognitive and neurological symptoms than controls from the general population.

Uma comparação das regulações de trabalho relacionadas à proteção da saúde no setor petroleiro do Brasil e da Noruega / A comparison of regulations on work related health in the petroleum sector in Brazil and Norway

Este trabalho apresenta um estudo comparativo das principais características dos modelos de regulação adotados em assuntos relacionados à saúde do trabalhador no setor petroleiro no Brasil e na Noruega. As legislações de ambos os países estão inseridas na tradição da lei escrita, mas cada nação tem uma abordagem particular de sua regulação. O Brasil conta com uma típica postura regulatória, enquanto a Noruega apresenta traços do direito consuetudinário, com modelos legais baseados na presunção de que as partes envolvidas são capazes de agregar boas e seguras práticas profissionais. Percebe-se que ambas as abordagens regulatórias relacionam-se com o panorama social de cada nação. Porém, como o tempo e a cultura se modificam, os dois países talvez tenham algo a aprender um com outro.

Spirometric Pulmonary Function Test in Preschool Children

Children aged 3~5 years old represent the challenge in pulmonary function assessment, since evaluating lung function in preschool age group is important for the appropriate treatment for patient with chronic and recurrent cough and wheeze during this period. The joint American Thoracic Society/European Respiratory Society task force has produced recommendations for the spirometric lung function test currently used in the preschool age group. The reliable scientific evidence, documented references and reviews by the experts were used as a support. Reference data of spirometry lung function in preschool children were available in several countries including USA, Norway, Czech, Israel, Canada, and Taiwan. Spirometric pulmonary function tests are feasible in 3~ to 5~year~old children. However, the existing data are not sufficient to make definitive recommendations. Recommendations will need to be revised periodically until sufficient evidence has been collected to make definitive guidelines in various situations.

Long-Term Acceptance of Fully Mhc-Mismatched Limb Allografts after a Short Course of Anti-alpha beta-T Cell Receptor Monoclonal Antibody and FK506

Whether a seven days course of anti-alpha beta cell receptor-antibody (alpha beta-TCRmAb) combined with FK506 therapy promotes survival of limb allografts in fully MHC-mismatched combination (Brown Norway --> Lewis) was examined. Eight animals received 250 microgram/kg/day of alpha beta-TCRmAb for 7 days and 2 mg/kg/day of FK506 postoperatively (Combination therapy group). Eight animals had FK506 only (Mono-therapy group) and five animals did not have treatment (Control group). Clinical signs of early rejection with edema or erythema in the skin occurred at an average of 8.6+/-1.5 days postoperatively in Control group and 59.0+/-8.3 days in Mono-therapy group, both of which proceeded to irreversible rejection with necrosis of the epidermis and finally mummification. In Combination therapy group, all animals showed evidence of early rejection at an average of 56.8+/-12.6 days postoperatively, however, in 4 of 8 limbs, early rejection resolved without any treatment and limbs survived >1 year. At 9 months postoperatively, donor skin grafts were accepted and third-party skin grafts were rejected by all four survivors, demonstrating donor-specific tolerance. Little or no detectable chimerism was observed in any of the 4 surviving animals at one-year postoperatively. Combination therapy of alphabeta-TCRmAb and FK506 resulted in long-term survival in fully MHC-mismatched limb transplants.

A Survey on the Mode of Working of Estheticians in OECD Member Nations andSome Asian Countries in Relation to Medical Service / 대한피부과학회지

In 2008, Korea has enacted new ordinances about the role of estheticians, but this law can be interpreted ambiguously, restricting hiring of estheticians in medical clinics. The purpose of the study is to obtain information about medical-esthetic systems in other countries. We have taken a survey of this object from 30 OECD & Asian countries, and the questionnaires returned from a total of 22 countries (Australia, Austria, Canada, Denmark, Finland, France, Germany, Hungary, Japan, Netherlands, New Zealand, Norway, Portugal, Slovak Republic, Spain, Switzerland, Turkey, United Kingdom, United States, Singapore, Israel, and Thailand), were used for the final analysis. The results are summarized as follows. In most countries, estheticians working independently deal with only healthy, normal skin. In most countries, estheticians working independently have no right to operate any medical instruments. In all 17 countries that returned the questionnaires medical clinics can employ estheticians, and only theses estheticians who belong to the medical clinics can handle the non-invasive medical instruments under the supervision of doctors. In 17 countries that have related legal regulations, nurses, under the control of doctors, can perform wider range of duties in various settings than estheticians. The survey concludes that the duties of estheticians are closely related with medical skin care services and estheticians can perform various non-invasive medical procedures only under the control of doctors. From consulting a variety of medical-esthetic systems in other countries, we propose that the estheticians be allowed to work in medical clinics to provide better medical services for the patients and to make more chances of employment for themselves.

Breve cotejo sobre o papel do ombudsman da saúde norueguês e a atuação do Ministério Público em defesa do direito à saúde no Brasil / Short considerations on the role of Norway health ombudsman and the defense of the right to health by the Prosecuting Counsel in Brazil

O artigo apresenta um paralelo entre o sistema de ombudsman da saúde na Noruega e a atuação do Ministério Público brasileiro, no que concerne à defesa dos direitos à saúde dos cidadãos. Para tanto, apresenta-se a opção do constituinte brasileiro de atribuir funções de ombudsman ao Ministério Público; em seguida, a forma de atuação desta instituição no Brasil, e, por fim, a comparação entre as características mais significativas das duas instituições.

O ombudsman do paciente: a experiência norueguesa / The patient ombudsman: the norwegian scheme

Para facilitar a implementação prática das leis referentes aos direitos dos pacientes, alguns países da Europa criaram o sistema de Ombudsman do Paciente. A Noruega foi uma das primeiras nações a adotar essa figura, há 20 anos, e hoje, conta com um ombudsman em todos os 19 condados (estados). A partir de 2001, a instituição do Ombudsman do Paciente adquiriu bases legais com o decreto dos Direitos dos Pacientes. O papel principal deste profissional é o de salvaguardar os pacientes e contribuir para a melhoria da qualidade dos serviços de saúde. Para tanto, oferece orientações, ajuda a esclarecer questões de saúde e apresenta casos para as autoridades públicas e para o sistema econômico de compensação. Com base na experiência européia e, em particular, norueguesa, este artigo discute a estrutura organizacional, papéis e funções do esquema de Ombudsman do Paciente.

As demandas de proteção da sociedade e os direitos individuais na legislação de saúde: exemplos da Noruega / Trade-offer between protective needs of society and individual rights in health legislation: examples from Norway

Este artigo apresenta a legislação atual relacionada ao tratamento compulsório de pacientes com desordens psiquiátricas e as medidas contra ameaças de transmissão de doenças para a saúde na Noruega. O papel do profissional médico é destacado e analisado considerando procedimentos previstos na legislação. O trabalho mostra as necessidades de procedimentos que são usadas para proteger os direitos individuais dos pacientes e o julgamento profissional em cada situação, dirigido pelo quadro legislativo.

The socio-economic impact of noise: a method for assessing noise annoyance.

Norwegian authorities have developed and adopted a method for assessing the magnitude of noise impact on a community in quantitative terms. The method takes into account all levels of noise annoyance experienced by all the residents in an area and transforms these data into a single quantity that can also be expressed in monetary terms. This method is contrary to other commonly used assessment methods where only a certain fraction of the impacted people, e.g. those "highly annoyed," is considered.